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A Controlled Substance for Anxiety Relief Diazepam, commonly known by the brand name Valium, is a prescription medication used to treat anxiety disorders, muscle spasms, and seizures. Classified as a benzodiazepine, it works by enhancing the effects of a natural chemical in the brain called GABA, which induces calming effects. In the U.S., it is a Schedule IV controlled substance due to its potential for abuse and dependence. Patients should use it only under a healthcare provider's supervision, with care taken to avoid prolonged usage.